This is a list of real life people who appeared in Animeme once as a guest role and are not regulars.
- Shane Dawson- Nyan Cat
- Tay Zonday- Old Spice Guy
- Toby Turner/Tobuscus- Courage Wolf
- Timothy DeLaGhetto- Psy
Tay Zonday, a youtuber known for his deep voice and musical talent.
Toby Turner, a well known comedian and actor.
Shane Dawson, another well known actor, vlogger, and comedian.